HIV-positive patient in Brazil “cured” thanks to a cocktail of pharmaceutical drugs

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Posted: Wednesday July 8, 2020 1:40 PM CST.

By Aaron Humes: Could the right mix of drugs eliminate a pandemic worse than COVID-19?

According to the Daily Mail (UK), the very first case of long-term remission of the human immunodeficiency virus (HIV), the virus that causes acquired immunodeficiency syndrome (AIDS), only as a result of pharmaceutical treatment, has been recorded.

A man from Sao Paulo, Brazil, in his mid-30s, responded well after 48 weeks to an intense cocktail of AIDS drugs, including antiretroviral therapy, or ART, supplemented by additional antiretrovirals, plus a drug called nicotinamide, a form of vitamin B3. . A little over a year later, his DNA and cells were tested and tested for HIV negative.

Dr Ricardo Diaz of the University of Sao Paulo in Brazil, who co-led the study, told the Telegraph: “We cannot search the whole body, but according to the best evidence we have no infected cells. I think it’s very promising. This patient could be cured.

“This case is extremely interesting, and I really hope it can stimulate the search for a cure for HIV,” said Andrea Savarino, doctor at the Italian Institute of Health who co-led the trial. , in an interview with UK charity NAM AIDSmap. .

The researchers caution, however, that four other HIV-positive patients treated in the trial with the same intensified drug cocktail saw no positive effects.

“The result is very likely not to be reproducible,” said Dr Savarino. “It’s a very first (preliminary) experience and I’m not planning beyond that.”

As scientists rush to develop vaccines and treatments for COVID-19, the fight continues to find a cure for HIV.

HIV has infected more than 75 million people and killed nearly 33 million since the start of the AIDS epidemic in the 1980s.

Patients who have access to AIDS drugs are able to control the virus and control the disease, and there are many ways to stop its spread.

However, despite this, approximately 37 million people worldwide are currently living with HIV; a majority (25 million) of them live in Africa.

Hopes for a cure from AIDS have been bolstered in recent years by two separate cases of remission in men who are described by HIV physicians as “functionally cured”. These patients were treated with high-risk and complex bone marrow transplants.

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