Hypertension Drugs May Protect Against Type 2 Diabetes, Science News

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A large study has suggested that antihypertensive drugs may protect against type 2 diabetes. The study was published in the Lancet medical journal.

Medicines for blood pressure are already prescribed by doctors around the world to reduce the risk of heart disease. However, the link between these drugs and type 2 diabetes was previously unknown.

The study was carried out by the universities of Oxford and Bristol. In this study, 145,000 people were observed for 5 years. These people have participated in 19 global randomized clinical trials. Researchers found that a 5 mmHg reduction in systolic blood pressure resulted in an 11% reduction in type 2 diabetes risk.

In this study, researchers looked at the main blood pressure medications compared to a placebo. They found that angiotensin converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) had the strongest protective effect. These two types of drugs reduced the risk of developing diabetes by 16 percent.

Other types of blood pressure lowering drugs have not been shown to be as effective. Medicines like calcium channel blockers have had no effect on type 2 diabetes.

The study was funded by the Oxford Biomedical Research Center of the British Heart Foundation’s National Institute for Health Research (NIHR) and the Oxford Martin School.


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