List of “Drugs to avoid in 2022” published by the French medical journal


The annual list of drugs to avoid in France was published by the medical journal Prescrire, the 105 drugs included being considered too high risk of side effects. Of these, 89 are still available.

The new annual list is the tenth published by Prescrire, an independent, nonprofit, subscription-funded medical publication. The post was one of the first to report issues with the weight loss drug Mediator.

Read more: French pharmaceutical company found guilty of diet pill linked to 2,000 deaths

The list features drugs that she believes should not be prescribed because they carry too many risks of side effects compared to any positive effects they might have.

Although part of the list concerns drugs that are not already marketed in France, 89 of the 105 drugs mentioned are still readily available.

These include some common treatments.

decongestants and cold medicine

  • Dolirhume
  • The Actifed range
  • Humex Rum

These are considered to cause a cardiovascular risk disproportionate to their usefulness. Their use is officially discouraged.

Sore throat


Analgesics and anti-inflammatory drugs

  • Voltarene
  • Any drug name ending in “coxib”
  • Qutenza patch

Instead, the review recommends the occasional use of paracetamol when possible.

Type 2 diabetes

These are considered to cause a risk of side effects, including allergic reactions, urinary tract infections, pancreatitis or intestinal blockages. The review said there was “not enough perspective yet” on their usefulness.

The drug metformin should remain “the gold standard,” he said.

And two drugs that are no longer on the list …

  • Gliflozins (such as Forxiga or Jardiance) – a sodium-glucose-2 co-transporter inhibitor (SGLT2), used to treat diabetes.

Previously perceived risks of kidney and heart failure and other problems are considered to have diminished after further assessments. However, Prescrire still does not actively recommend the use of the drugs, due to a persistent risk of side effects such as severe infections and skin reactions.

  • Cimetidine – a histamine that inhibits the production of stomach acid.

This drug is no longer on the list because it is no longer available, after a global recall.

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